Wednesday October 1, 2008


Q: Propofol may lower the serum concentration of which essential element?

A: Zinc

Propofol treated patients have shown greater urinary losses of zinc and iron and to lower serum zinc concentrations. But the clinical significance of trace metal losses is unclear and requires further study.



Reference: click to get abstract

1. Trace element homeostasis during continuous sedation with propofol containing EDTA versus other sedatives in critically ill patients - Intensive care medicine Supplement 2000, vol. 26, n4, pp. S413-S421 (30 ref.)